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Xenical General information Page
Xenical (pronounced: zen-i-cal) is a prescription medication, taken orally, that helps people struggling with obesity lose fat and keep it off. Xenical, when taken with a meal, blocks about 30% of the fat that is ingested along with the meal. By reducing obesity, Xenical helps to reduce the chance of strokes, heart disease, high blood pressure and osteoarthritis that are commonly linked to obesity.  
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Xenical 120mg Tablets

What is Xenical

Xenical is an oral prescription weight loss medication used to help significantly overweight people lose weight and keep this weight off. Xenical should be used together with a reduced-calorie diet.

How does Xenical work?

When you eat fat, your body breaks it down into its simplest components so that it can be absorbed. Enzymes in your intestinal tract, called lipases, help digest (or breakdown) fat. When you take Xenical with meals, Xenical attaches to the lipases and blocks them from breaking down some of the fat you have eaten. The undigested fat cannot be absorbed and is eliminated in your bowel movements. This way, Xenical helps block about 30% of the fat eaten in food from being absorbed by your body.

Who should use Xenical

Xenical is recommended for people who are considerably overweight (at least 30% above ideal weight or a body mass index of 30 or greater). Xenical may also be used by overweight people (at least 20% above ideal weight or a body mass index of 27 or greater) and also have other risk factors such as high blood pressure, high cholesterol, heart disease, or diabetes.

What is BMI?

The most widely used measurement of obesity has been the Body Mass Index or BMI.
It is calculated as the weight in Kilograms divided by the square of the height in meters
This value is independent of age or sex.

Its use is not intended for children, pregnant women and very muscular individuals such as athletes.

Who should not use Xenical?

Xenical should not be taken if you are pregnant or nursing, have food absorption problems such as chronic malabsorption syndrome. If you suffer from gall bladder problems or have ever had an allergic reaction to orlistat or any of the inactive ingredients in Xenical.

Consult your doctor before using Xenical if you suffer from hypothyroid or are taking cyclosporine.

What should I tell my doctor before taking Xenical?

Before beginning treatment with Xenical, make sure your doctor knows if you are:

  • Allergic to any medicines, foods, or dyes.
  • Taking any other weight-loss medication.
  • Taking cyclosporine.
  • Taking any other medicines (including those not prescribed by your doctor)
  • Taking any dietary supplements, including herbal products
  • Planning to become pregnant
  • Suffer from eating disorders such as anorexia or bulimia.

This information will help you and your physician decide if the expected advantages of Xenical are greater than any possible disadvantages.

How much and when?

The recommended dose is one 120 mg capsule taken orally with liquid at each main meal that contains fat. You may take Xenical in conjunction with a mildly reduced-calorie diet up to 3 times a day. Xenical should be taken during meals or up to one hour after a meal. If you miss a meal or it contains no fat, the dose of Xenical may be omitted.

You should use Xenical together with a nutritionally balanced, calorie-controlled diet that is rich in fruit and vegetables and contains no more than about 30% of calories from fat. You should evenly divide your daily intake of fat, carbohydrates, and protein over 3 main meals.

If you forget to take your medication at any time, take it as soon as you remember provided this is within one hour of your last meal, then continue to take it at the usual times. Do not take a double dose. If you miss several doses, please inform your doctor and follow the advise given to you.

Should I take a multivitamin with Xenical?

Xenical interferes with your body’s absorption of some fat-soluble vitamins. Therefore, when you use Xenical, you should take a daily multivitamin supplement that contains vitamins D, E, K, and beta-carotene. Take your multivitamin once a day at least 2 hours before or after taking Xenical, such as at bedtime.

What are the most common side effects of Xenical?

Because Xenical works by blocking the absorption of dietary fat, it is likely that you will experience some changes in bowel habits. These generally occur at the beginning of treatment and may include oily spotting, gas with discharge, urgent need to go to the bathroom, oily or fatty stools, an oily discharge, increased number of bowel movements, and inability to control bowel movements. Due to the presence of undigested fat, the oil seen in a bowel movement may be clear or have coloration such as orange or brown.

Maintaining the recommended dietary regimen containing no more than 30% of calories from fat may minimize the occurrence of these events.

Where do I keep it?

Store at controlled room temperature 59° to 86° F (15° to 30° C)

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